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Ving Rhames - Animal, Terrence Howard - Darius Allen, Chazz Palminteri - Kassada, Jim Brown - Berwell, Beverly Todd - Latreese, Faizon Love - Double T, Wes Studi - Creeper, Paula Jai Parker - Reecy, Taraji P. Henson - Ramona, César Farrait - Roach (as Cessar 'TNT' Farrait) , Modesto Lacen - Dinky, Black Child - Spyda, Hunter Howard - Young Darius, Rafael Alvarez - Paul Wilson (as Rafa Alvarez) , Eugenio Cotto - Assassin 1 - Berwell (as Eugene Cotto)